Bone Sarcoma

Bone sarcomas are those which arise from, or within, the bones and/or cartilage of the skeleton. There are three 'common' bone sarcomas which have different epidemiological, clinical and pathological features.

Characteristic Osteosarcoma Chondrosarcoma PNET
Age of Onset Teens; 30% of cases over 40 Mostly over 50 Teens; almost no cases over 30
Gender Significant male excess Almost even Significant male excess
Race No factors identified No factors More common in European/Hispanic; very rare in Africans
Symptoms Weeks Months-years Weeks
Microscopy Osteoid deposits, pleomorphic Irregular lobules of chondrocytes that permeate the bone Small round blue cell tumour