Bone Sarcoma
Bone sarcomas are those which arise from, or within, the bones and/or cartilage of the skeleton. There are three 'common' bone sarcomas which have different epidemiological, clinical and pathological features.
| Characteristic | Osteosarcoma | Chondrosarcoma | PNET |
|---|---|---|---|
| Age of Onset | Teens; 30% of cases over 40 | Mostly over 50 | Teens; almost no cases over 30 |
| Gender | Significant male excess | Almost even | Significant male excess |
| Race | No factors identified | No factors | More common in European/Hispanic; very rare in Africans |
| Symptoms | Weeks | Months-years | Weeks |
| Microscopy | Osteoid deposits, pleomorphic | Irregular lobules of chondrocytes that permeate the bone | Small round blue cell tumour |
