Diagnosis

History

Presenting Complaint

The most common presenting symptom is pain (90% of cases), usually related to the site of the tumour. Patients may also complain of a lump in the region. About 40% of patients have tumour arising from the axial skeleton (ribs, vertebrae or pelvis). 25% arise in the upper limbs and 35% in the lower limbs. A variety of Ewing sarcoma that arises from the ribs and extends into the pleura is named an Askin tumour after it was described in 1979.
Uncommon symptoms include:

  • Neurological (due to peripheral nerve involvement or spinal cord compression) in 15% of patients
  • Fever in 10% of patients. This is associated with large tumour volumes and metastases.

Past History

Medications

Allergies

Family History

Social History


Examination


Imaging

CT and MRI have revolutionised the treatment of Ewing Sarcoma/PNET, particularly for the radiation oncologist. Both scans are helpful in determining the local extent of the tumour; CT has additional roles in demonstrating the presence of haematogenous spread.


Histological Diagnosis


Staging


Links


Bibliography

Bibliography
1. full source reference