Systemic Therapy

Myeloid sarcoma is usually found together with acute myeloid leukaemia; treatment of the leukaemia usually treats the myeloid sarcoma as well.


Radiotherapy can be used in settings where chemotherapy is not appropriate, available or effective.

The typical dose is 24 Gy in 12 fractions which provides long term local control in the majority of patients. There is no randomised data. The tumour is usually exquisitely sensitive to radiotherapy. Consider tumour lysis prophylaxis if the tumour is very large.