Systemic Therapy

Systemic therapy is required for metastatic basal cell carcinoma. This is a very rare diagnosis but does occur due to the high prevalence of BCCs in the community. About 300 cases are reported in global literature.

For a good summary, see Ganti and Kessinger. Systemic therapy for disseminated basal cell carcinoma: An uncommon manifestation of a common cancer. Cancer treatment reviews (2011)

Chemotherapy

Most evidence suggests that platinum-based chemotherapy is most appropriate